How to Use / Administration Methods
MT-II is administered via subcutaneous injection into abdominal fat, the thigh, or the deltoid region. It is supplied as a lyophilized powder requiring reconstitution before use.
Injection Procedure:
- Clean the injection site with an alcohol swab
- Pinch a skin fold to isolate subcutaneous tissue
- Insert needle at a 45–90 degree angle
- Inject solution slowly
- Withdraw the needle and apply gentle pressure
Insulin syringes (29–31 gauge, 0.5–1 mL) are commonly used for administration. Rotating injection sites is recommended to prevent lipodystrophy.
Nasal spray formulations exist but have significantly lower and less predictable bioavailability than subcutaneous injection, and are generally not favored by experienced users.
Reconstitution, Storage & Prep
MT-II is supplied as sterile lyophilized powder, typically in 10 mg vials.
Reconstitution Process:
- Allow vial to reach room temperature
- Using a sterile syringe, draw bacteriostatic water (preferred) or sterile water
- Inject water slowly down the inside wall of the vial, do not spray directly onto powder
- Gently swirl (do not shake) until fully dissolved
- The solution should be clear and colorless; do not use if cloudy or particulate matter is visible
Common Reconstitution Ratio:
- 10 mL bacteriostatic water added to a 10 mg vial yields 1 mg/mL (100 mcg per 0.1 mL / 10 units on an insulin syringe)
Storage Guidelines:
- Unreconstituted powder: Refrigerate (2–8°C) or freeze; stable for 12+ months
- Reconstituted solution: Refrigerate at 2–8°C and use within 4–6 weeks
- Protect from light; avoid repeated freeze-thaw cycles
- Do not use if solution appears cloudy or contains visible particles